The Legend: Blotter LSD doses on the bottom of the sheet are stronger.
Status: False
Analysis
This one is interesting. It is said that when LSD is manufactured, the sheet of perforated blotter paper is soaked in a pan of LSD solution. After the LSD is absorbed the sheet is hung to dry, presumably clipped to a line like how you would dry photographs. While hanging, the LSD solution is pulled to the bottom of the blotter paper, leaving the doses along the bottom significantly stronger and the doses along the top weaker.
This makes sense, if LSD were actually manufactured in this way. The definitive text on LSD manufacture is an underground book called Practical LSD Manufacture (1995) written by the pseudonymous Uncle Fester. In this book it is explained in great detail that manufacturing LSD involves delivering a single carefully measured droplet from the tip of a burette onto each sugar cube or perforated square of blotter paper. No wetting pans or clotheslines are involved.
To support this manufacturing process, the Drug Enforcement Administration (DEA) reports that virtually all of the LSD that they have seized and tested has been of relatively uniform dosages. Assuming the DEA's LSD seizures have included doses from both the top and bottom of sheets of blotter, if the hits at the bottom were indeed stronger then there would be greater disparity in their reported dosage levels, and there isn't.